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FELODIPINE

FELODIPINE

(Synonyms:3,5-pyrinedicarboxylic acid; 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-
ethyl methyl ester; (±)-(±)-ethylmethyl; 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-
dimethyl-3,5-pyridinedicarboxylate)

CAS Rn72509-76-386189-69-7

Molecular FormulaC18H19Cl2NO4

Molecular Weight384.2538

Quality Standard[USP25]

AInfrared Absorption

AppearanceLight yellow or white crystals

Assay98.0%~101%

Density1.277g/cm3

Melting Range:142-145℃

Boiling Point471.5°C at 760 mmHg

Flash Point239°C

Vapor Pressure4.62E-09mmHg at 25°C

Loss on drying≤0.5%

Residue on ignition≤0.1%

Heavy Mental0.002%

Chromatographic Impurity

Individual Impurity≤1.0%

Total Impurity≤1.5%

Indications and usage:

For patients with hypertension, ischemic heart disease and heart failure

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